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mavacamten will lessen the extent or outcome of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Progestin and ethinyl estradiol are CYP3A4 substrates. Mavacamten may perhaps lessen systemic exposures of ethinyl estradiol and progestin, which may bring on contraceptive failure or a ri